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KMID : 0388219950020020187
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Journal of the Korean Rheumatism Association
1995 Volume.2 No. 2 p.187 ~ p.191
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A Case of Primary Sjoren Symdrome Presenting as Adie’s Syndrome
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Kim Seon-Hee
Kim Young-Hak
Cho Yoo-Sook
Kim Chan
Choi Seung-Won
Yoo Bin
Lee Myoung-Chong
Moon Hee-Bom
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Abstract
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Sjoren’s syndrome is a heterogenous autoimmune disease characterized by progressive destruction of the exocrine glands and accompanied by a variety of autoimmune phenomena. Sjoren’s syndrome patients can develop symptoms of ocular and oral dryness as well as extralandular complications including central and peripheral nervous system disease.
Sometimes neuropathy precedes the diagnosis of Sjoren’s syndrome. Adie’s syndrome is characterized by tonic pupil and the absence of tendon reflex. Sweating abnormaltiy and chronc peripheral polyneuropathy can also be present. We report a case of primary Sjoren’s syndrome precede by Adie’s syndrome with peripheral neuropathy. A 26-year-old woman was admitted for photophobia and paresthesia. On examination, her pupils were anisocoric and did not react to light but constricted dpromptly to pilocarpin. Sensatin decreased on her left side of body and deep tendon reflexes were absent. Biopsy of minor salivary gland demlonstr4ated infilatration by lymphocyte consistent with Sjoren’s syndrome, but Schirmer test was negative. So she was diagnosed as Adie’sd syndrome with peripheral neuropathy. Five month later she complained of dry eye and dizziness. Rose bengal staining was positive. Sj?ren’s syndrome was diagnosed and she was discharged with local therapy for therapy for the sicca symptoms.
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KEYWORD
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Sjogren’s syndrome, Adie’s syndrome
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